Groupe de recherche clinique en anesthésie réanimation médecine périopératoire (GRC ARPE)

• Article dans une revue

Cost-utility of point-of-care viscoelastic hemostatic assays in the management of bleeding during cardiac surgery: A single-blinded prospective multicenter stepped wedge cluster randomized trial in French context

Mickael Vourc’h, Elodie Boissier, Karim Lakhal, Sandrine Grosjean, François Labaste, Emmanuel Robin, Adrien Bougle, Mathieu Mattei, Jérôme Morel, Véronique Wurtz, Paul-Michel Mertes, Diane Zlotnik, David Lagier, Antoine Beurton, Emmanuel Rineau, Marc-Olivier Fischer, Marc-Antoine May, Anne Médard, Guillaume Guimbretiere, Isabelle Durand-Zaleski, Morgane Pere, Bertrand Rozec, Jean-Christophe Rigal

Background: The IMOTEC study aims to determine whether a point-of-care viscoelastic hemostatic assay (VHA)-guided algorithm is cost-effective for the management of ongoing bleeding. Methods: Stepped wedge cluster randomized trial, patient blinded, conducted at 16 French academic cardiac surgery…

Anaesthesia Critical Care & Pain Medicine, 2026, 45 (3), pp.101704. ⟨10.1016/j.accpm.2025.101704⟩. ⟨hal-05568137⟩

• Article dans une revue

Deep white matter MRI predicts outcomes in coma of various etiologies: a cohort study

Louis Puybasset, Pierre Siméone, Martin Grange, Didier Cassereau,, Damien Galanaud, Rémy Bernard, Lionel Velly, Vincent Perlbarg, Clément Capdeville, Valentine Battisti, Lamine Abdennour, Adrien Bouglé, Jean-Michel Constantin, Antoine Monsel, Juliette Chommeloux, Julien Mayaux, Benjamin Rohaut, Lionel Naccache, Alice Jacquens, Vincent Degos, Mélanie Pélégrini-Issac

Background A reliable outcome prognostication tool for patients in coma of various etiologies would facilitate ICU treatment by providing objective information to caregivers and patients' relatives. This study aimed to predict outcome based on supervised machine learning and magnetic resonance…

Critical Care, In press, ⟨10.1186/s13054-026-05909-x⟩. ⟨inserm-05600660⟩

• Article dans une revue

Correction: Discarded intravenous medication in the ICU: the GAME-OVER multicenter prospective observational study

Erwan d'Aranda, Stéphanie Pons, Jonathan Chelly, Enora Atchade, Laure Bonnet, Claire Dahyot-Fizelier, Toufik Kamel, Fanny Giannoni, Olivier Collange, Emmanuel Besnier, Mathieu Schoeffler, Nicolas Mayeur, Pierre-Louis Quere, Ludivine Marecal, Cyril Pernod, Cyrille Geay, Pierre Esnault, Raphaël Cinotti, Magali Cesana, Pierre-Julien Cungi

Critical Care, 2026, 30 (1), pp.32. ⟨10.1186/s13054-025-05822-9⟩. ⟨hal-05529724⟩

• Article dans une revue

Levosimendan to Facilitate Weaning From ECMO in Patients With Severe Cardiogenic Shock

Alain Combes, Ouriel Saura, Nicolas Nesseler, Said Lebbah, Bertrand Rozec, Bruno Levy, Jean-Luc Fellahi, Antoine Beurton, Simon Meslin, Philippe Gaudard, Adrien Bouglé, André Vincentelli, Romain Sonneville, Guillaume Lebreton, David Lévy, Alexandre Ouattara, Florence Tubach, Juliette Chommeloux, Grégoire del Marmol, Guillaume Hekimian, Pascal Leprince, Charles-Edouard Luyt, Quentin Moyon, Marc Pineton, Matthieu Schmidt, Nima Djavidi, Corinne Batsale, Thibaud Besnard, François-Xavier Hérion, Julien Imbault, Laure Maudiere, Claire Oddos, Mathieu Pernot, Simon Veyret, Najla Dachraoui, Florence Gimbert, Hélène Nougue, Paul Achouh, Bernard Cholley, Delphine Chesnel, Léa Didier, Matthias Jacquet-Lagreze, Martin Ruste, Joseph Pierre, Aurore Ughetto, Hélène David, Marc Mourad, Cinderella Blin, Sebastien Biedermann, Xavier Buzin, Erwan Flécher, Grégoire Le Gac, Alexandre Mansour, Antoine Kimmoun, Pierre Perez, Clement Haddadi, Carine Thivillier, Thomas Klein, Arthur Bailly, Philippe Bizouarn, Julien Cadiet, Nicolas Groleau, Thierry Lepoivre, Johanna Nicolet, Fouzia Souab, Mickaël Vourc'H, Marie Jungling, Etienne de Montmollin, Lila Bouadma, Jean-François Timsit, Michael Thy, Julien Dessajan

Importance: Levosimendan may facilitate weaning from venoarterial extracorporeal membrane oxygenation (VA-ECMO) and improve survival, but supporting evidence remains limited.Objective: To assess whether early administration of levosimendan reduces the time to successful VA-ECMO weaning in patients…

JAMA Cardiology, 2026, 335 (1), pp.60. ⟨10.1001/jama.2025.19843⟩. ⟨hal-05392447⟩